Canadian Manufacturing

Innovation Minister excited about Canada’s biomanufacturing sector

The government spent billions of dollars in an attempt to rebuild Canada's flagging biomanufacturing capabilities as quickly as possible, after decades of decline.

December 7, 2021  The Canadian Press

Innovation Minister Francois-Philippe Champagne says Canada’s biomanufacturing sector has rebounded beyond his initial expectations in the last several months, as a Canadian drug maker stands poised to bring positive results from the first plant-based COVID-19 vaccine to Health Canada.

At the outset of the pandemic, Canada’s lack of biomanufacturing capability came into sharp focus, and the incapacity to produce COVID-19 vaccines domestically caused some major initial stumbles in the country’s early vaccine rollout.

Champagne says his vision was to rebuild the sector based on the different families of vaccines, as well as improve the capacity for contract manufacturers in Canada.

“This is beyond my expectations,” Champagne said in an interview on Dec. 6.

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The government spent billions of dollars in an attempt to rebuild Canada’s flagging biomanufacturing capabilities as quickly as possible, after decades of decline.

Canadian company Medicago benefited from its largest investment, $173 million, to support the development of a plant-based COVID-19 vaccine and establish a large-scale manufacturing plant.

Now, Medigaco is churning out doses of its made-in-Canada vaccine in anticipation of its application to Health Canada, after trials showed the drug is 75.3 per cent effective against the Delta variant of COVID-19.

The company announced its trial results on Dec. 7, citing 88.6 per cent efficacy against the Gamma variant of COVID-19, and 75.3 per cent efficacy against Delta.

Medicago plans to take those results to Health Canada before the end of the year, as well as regulators in the United Kingdom, the United States, the World Health Organization and eventually Japan.

It has already started building inventory, 75 million doses of which have been promised to Canada.

Champagne’s plan to have several types of COVID-19 vaccine produced in Canada appears to be coming together.

Moderna and BioVectra are set to manufacture mRNA technology in Canada. If Medicago gets a green light from Health Canada, it will produce its plant-based vaccines. Novavax has already filed for regulator approval of its protein based vaccine, which will be manufactured in the National Research Council’s Biologics Manufacturing Centre in Montreal. Sonofi will spend $925 million to build a new vaccine facility in Toronto to bolster manufacturing capacity.

And just yesterday Merck Canada announced it inked a deal with Thermo Fisher Scientific to manufacture the oral antiviral COVID-19 treatment, molnupiravir, at its facility in Whitby, Ont. with a mandate to supply the product domestically, as well as to the United Kingdom, European Union, Asia Pacific and Latin America.